Takara Bio USA has launched the Smart-Seq Pro kit for the ICell8 cx single-cell system.
This automated single-cell RNA-seq solution allows researchers to generate full-length transcriptome data from over 1,500 single cells simultaneously, from a wide range of sample types. The kit can generate transcriptome data from eight at samples at a time.
PerkinElmer and Honeycomb Biotechnologies have commercially launched the HIVE scRNAseq Solution for single-cell isolation analysis. The product is a portable, handheld device for the capture, storage, and RNA-seq library preparation of a diverse range of cell types, including fragile and labile cells such as granulocytes, nephrons, hepatocytes, and neurons, the companies said. HIVE integrates sample capture and preservation into a single-use device, making it possible to collect samples from multiple sites and maintain sample integrity during storage, shipping, and processing from a central testing lab, which is particularly important for multi-center studies, the companies said. Cells are gently loaded by gravity in volumes up to 4 mL, enabling capture of fragile cell types and processing of sparse samples such as fine needle aspirates, cytobrushes, and flow-sorted cells.
EliTechGroup has launched a CE-IVD marked, standalone, sample-to-result RT-PCR testing system called the Elite BeGenius. The system boasts a compact footprint, ease-of-use, and total automation, and performs up to 24 tests per run.
Lybe Scientific, a startup commercializing nanoparticle-based technology developed at the Norwegian University of Science and Technology, has launched its first product with CE marking, the NAxtra nucleic acid extraction kit, a magnetic bead-based technology intended for viral RNA extraction from human nasopharyngeal and/or oropharyngeal swab samples. The kit should be used for the isolation and purification of viral RNA when preparing clinical samples for downstream molecular diagnostics, and is intended for use by clinical laboratory personnel specifically instructed and trained in magnetic bead-based nucleic acid purification and in vitro diagnostic procedures, the company said.
CareDx has launched AlloSure Lung. AlloSure, the company's donor-derived cell-free DNA test for noninvasive transplant surveillance, is available for assessing kidney and heart transplantation. It will now also be available for use in lung transplantation.
NanoString Technologies has announced the launch of an antibody drug conjugate (ADC) panel for its nCounter platform. The new panel offers customizable content to help evaluate ADC's throughout discovery, pre-clinical, and clinical studies. It can profile 770 genes relevant to ADC development, including tumor targeting and antigen expression, internalization, payload release, drug mechanism of action, target cell death, immunogenic cell death, and mechanisms of resistance.
Sophia Genetics has introduced version 3 of its Clinical Exome Solution application. The new release features a capture-based target enrichment kit as well as what the company said is "enhanced" probe design for better detection of Mendelian diseases from within the entire mitochondrial genome and noncoding variants in 280 specific genomic locations.
Versiti this week announced the creation of a new assay for transplant patients that detects and characterizes genomic loss of heterozygosity (LOH) in the human leukocyte antigen (HLA) region. The assay, from the Versiti Histocompatibility Lab, consists of flow cytometric enrichment of a patient's cancer cells, followed by genomic analysis. Versiti uses two separate genomic analysis methods to better ensure accurate detection of HLA LOH. The company has partnered with Seattle-based HematoLogics to identify and isolate abnormal cells in relapse samples via flow cytometry and cell sorting.
Cytek Biosciences has launched a 25-color immunoprofiling assay to enable a more comprehensive understanding of the human immune system through full-spectrum flow cytometry. The assay is optimized for use with Cytek's Aurora full-spectrum flow cytometer equipped with violet, blue, yellow-green, and red lasers, and provides a turnkey solution for identifying major human immune subpopulations for T, B, and NK cells; as well as monocytes, dendritic cells, and basophils. To support the new assay, Cytek released an 18-color cFluor reagents kit that can be used with seven reagents from other suppliers.
Crown Bioscience, a JSR Life Sciences company specializing in contract biopharmaceutical R&D, has launched its 3D Ex Vivo Patient Tissue Platform. Using freshly collected patient tumor material, this new service can accurately measure oncology and immuno-oncology drug-induced tumor killing and endogenous immune cell proliferation, the company said. The technology aims to improve clinical success rates by using the most patient-relevant tumor samples to better predict tumor response to potential drug candidates. The automated high-throughput platform uses high-content 3D imaging and image analysis to quantify distinct responses of individual cell populations in fresh patient tissues. These analyses can assess responses to different doses of therapeutic candidates at various timepoints and can determine the effects of the drug or combination of drugs on tumor killing and immune cell proliferation.