exome sequencing Exome Sequencing of UK Biobank Participants Highlights Natural Variation, Gene Function Regeneron Genetics Center researchers and their colleagues identified a number of protective gene-trait associations from the UK Biobank dataset. De Novo Mutations Linked to Male Infertility in Trio Exome Sequencing Study At the ASHG annual meeting this week, a Newcastle University researcher described efforts to find de novo mutations behind oligozoospermia or azoospermia. PLOS Papers on Angelman Syndrome-Like Cases, Salmonella Paratyphi A, SARS-CoV-2 in Brazil In PLOS this week: exome sequencing analysis of Angelman syndrome-like cases, genetic epidemiology of Salmonella Paratyphi A, and more. Mayo Clinic, Personalis Ink Comprehensive Genomics Research Collaboration Investigators intend to offer Personalis' comprehensive genomics testing to consenting patients for both clinical use and to aggregate data for ongoing research. Sequencing Study Points to Prenatal Development Syndrome, Possible Treatment Strategy With the help of sequencing, researchers identified several families affected by Zaki syndrome, caused by potentially targetable mutations affecting Wnt signaling. Sep 9, 2021 Blueprint Genetics to Analyze Biobank Samples for Rare Diseases in New Finnish Study Sep 7, 2021 Centogene Q2 Revenues Continue to Benefit From COVID-19 Testing as Core Business Starts to Recover Aug 18, 2021 Helix Study Identifies Additional Genes for Population Genetic Screening Premium Aug 12, 2021 Benign Hypertension-Causing Tumors Linked to Somatic Codriver Mutations Aug 11, 2021 Sema4, Avera Health Collaborate on Precision Oncology Program Aug 5, 2021 Lung Cancer Features, Treatment Clues Emerge From 'Omic Analysis of Difficult-to-Treat Subtype Jul 28, 2021 AbbVie, Biogen, Pfizer Join With Broad Institute on Genebass Exome Variant Project Premium Jul 9, 2021 Integrated Tumor, Microbiome Features Influence Immunotherapy Combo Effects in Advanced Melanoma Jul 9, 2021 Human Reference Genome Choice Impacts Variant Calling, but Switching Is Tricky Premium Jul 7, 2021 Rare Mutations Associated With Significantly Higher Risk of Type 2 Diabetes in New Study Jul 6, 2021 Imputation of UK Biobank Data Uncovers Rare Coding Variants Linked to Range of Traits Jul 1, 2021 ACMG Recommends Sequencing as Test for Children With Intellectual Disability, Congenital Anomalies Jul 1, 2021 Rare Variants in G Protein-Coupled Receptor Gene May Provide Protection From Obesity Jun 28, 2021 Obsessive Compulsive Disorder Exome Analysis Uncovers Contributions From Rare Coding Variants Jun 4, 2021 Breast Cancer Genomics Study Reveals Recurrent Contributors to Treatment Resistance in Early Disease Jun 3, 2021 Helix Raises $50M in Series C Financing May 20, 2021 Caris Life Sciences, National Cancer Center Japan Partner for New Arm of SCRUM-Japan Study May 20, 2021 Quantgene Attempts to Woo Consumers With Liquid Biopsy Cancer Risk Assessment Service Premium May 20, 2021 ACMG Updates Gene List for Labs Reporting Clinical Sequencing Secondary Findings May 7, 2021 NorthShore, Sema4 Partnership Aims to Demonstrate Utility of Genomics for Personalized Care Premium Load More Breaking News Exome Sequencing of UK Biobank Participants Highlights Natural Variation, Gene Function Cystic Fibrosis Sinus Infections Involve Microbes With Shifting Evolution Patterns Molecular Assemblies Wins $256K NIH Phase I SBIR Grant to Develop Enzymatic DNA Synthesis Vibrent Health, VCU Partner to Offer Twin Research Platform Castle Biosciences Acquires Cernostics for up to $80M Princess Margaret Cancer Centre, Inivata Partner on Clinical Liquid Biopsy Studies The Scan Could Mix It Up The US Food and Drug Administration is considering a plan that would allow for the mixing-and-matching of SARS-CoV-2 vaccines and boosters, the New York Times says. Closest to the Dog New Scientist reports that extinct Japanese wolf appears to be the closest known wild relative of dogs. Offer to Come Back The Knoxville News Sentinel reports that the University of Tennessee is offering Anming Hu, a professor who was acquitted of charges that he hid ties to China, his position back. PNAS Papers on Myeloid Differentiation MicroRNAs, Urinary Exosomes, Maize Domestication In PNAS this week: role of microRNAs in myeloid differentiation, exosomes in urine, and more.